Maciej J. Zamek-Gliszczynski: search on Z-Library

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1

Validation of 96-well equilibrium dialysis with non-radiolabeled drug for definitive measurement of protein binding and application to clinical development of highly-bound drugs

Maciej J. Zamek-Gliszczynski, Kenneth J. Ruterbories, Rose T. Ajamie, Enaksha R. Wickremsinhe, Lavanya Pothuri, Mukkavilli V. S. Rao, Vinay N. Basavanakatti, Jakir Pinjari, Vikram K. Ramanathan, Ajai

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 121 KB

english, 2011

2

How well do lipophilicity parameters, MEEKC microemulsion capacity factor, and plasma protein binding predict CNS tissue binding?

Maciej J. Zamek-Gliszczynski, Karen E. Sprague, Alfonso Espada, Thomas J. Raub, Stuart M. Morton, Jason R. Manro, Manuel Molina-Martin

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 409 KB

english, 2012

3

Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Ken-ichi Nezasa, Melanie N. Tallman, Kim L.R. Brouwer

Journal:

European Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 978 KB

english, 2006

4

Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity

Jin Kyung Lee, Elaine M. Leslie, Maciej J. Zamek-Gliszczynski, Kim L.R. Brouwer

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

5

Knocking Down Transport: Applications of RNA Interference in The Study of Drug Transport Proteins

Tian, Xianbin, Zhang, Peijin, Zamek-Gliszczynski, Maciej J., Brouwer, Kim L. R.

Journal:

Drug Metabolism Reviews

Year:

2005

Language:

english

File:

PDF, 218 KB

english, 2005

6

The Effect of Dolutegravir on the Pharmacokinetics of Metformin in Healthy Subjects

Song, Ivy H., Zong, Jian, Borland, Julie, Jerva, Fred, Wynne, Brian, Zamek-Gliszczynski, Maciej J., Humphreys, Joan E., Bowers, Gary D., Choukour, Mike

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2016

Language:

english

File:

PDF, 716 KB

english, 2016

7

Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites

Patel, Mitesh, Taskar, Kunal S., Zamek-Gliszczynski, Maciej J.

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 372 KB

english, 2016

8

Emerging Clinical Importance of Hepatic Organic Cation Transporter 1 (OCT1) in Drug Pharmacokinetics, Dynamics, Pharmacogenetic Variability, and Drug Interactions

Zamek-Gliszczynski, Maciej J., Giacomini, Kathleen M., Zhang, Lei

Journal:

Clinical Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 95 KB

english, 2017

9

Hepatobiliary disposition of atovaquone: A case of mechanistically unusual biliary clearance

Patel, Mitesh, Johnson, Marta, Sychterz, Caroline J., Lewis, Gareth J, Watson, Cory, Ellens, Harma, Polli, Joseph W., Zamek-Gliszczynski, Maciej J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 924 KB

english, 2018

10

ITC Commentary on Metformin Clinical Drug-Drug Interaction Study Design That Enables an Efficacy- and Safety-Based Dose Adjustment Decision

Zamek-Gliszczynski, Maciej J., Chu, Xiaoyan, Cook, Jack A., Custodio, Joseph M., Galetin, Aleksandra, Giacomini, Kathleen M., Lee, Caroline A., Paine, Mary F., Ray, Adrian S., Ware, Joseph A., Wittwer

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 273 KB

english, 2018

11

Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Zamek-Gliszczynski, Maciej J., Taub, Mitchell E., Chothe, Paresh P., Chu, Xiaoyan, Giacomini, Kathleen M., Kim, Richard B., Ray, Adrian S., Stocker, Sophie L., Unadkat, Jashvant D., Wittwer, Matthias

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 394 KB

english, 2018

12

Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition

Chu, Xiaoyan, Galetin, Aleksandra, Zamek-Gliszczynski, Maciej J., Zhang, Lei, Tweedie, Donald J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 350 KB

english, 2018

13

Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space

Unger, Melissa S., Mudunuru, Jennypher, Schwab, Matthias, Hopf, Carsten, Drewes, Gerard, Nies, Anne T., Zamek-Gliszczynski, Maciej J., Reinhard, Friedrich B. M.

Journal:

Molecular Pharmaceutics

Year:

2020

Language:

english

File:

PDF, 616 KB

english, 2020

14

Letter to the editor re

Romach, Elizabeth H., Stanislaus, Dinesh, Zamek-Gliszczynski, Maciej J.

Journal:

Year:

2020

File:

PDF, 110 KB

2020

15

Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space

Unger, Melissa S., Mudunuru, Jennypher, Schwab, Matthias, Hopf, Carsten, Drewes, Gerard, Nies, Anne T., Zamek-Gliszczynski, Maciej J., Reinhard, Friedrich B. M.

Journal:

Molecular Pharmaceutics

Year:

2020

File:

PDF, 616 KB

2020

16

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

Unger, Melissa S., Schumacher, Lena, Enzlein, Thomas, Weigt, David, Zamek-Gliszczynski, Maciej J., Schwab, Matthias, Nies, Anne T., Drewes, Gerard, Schulz, Sandra, Reinhard, Friedrich B.M., Hopf, Cars

Journal:

Analytical Chemistry

Year:

2020

File:

PDF, 635 KB

2020